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Volume 36 , Issue 6
November/December 2016
Pages 807–815

Tissue Integration of a Volume-Stable Collagen Matrix in an Experimental Soft Tissue Augmentation Model

Luca Ferrantino, DDS, MSc, PhD/Dieter Bosshardt, DDS, PhD/Myron Nevins, DDS/Giacomo Santoro, DDS/Massimo Simion, MD, DDS/David Kim, DDS, DMSc

PMID: 27740641
DOI: 10.11607/prd.3066

Reducing the need for a connective tissue graft by using an efficacious biomaterial is an important task for dental professionals and patients. This experimental study aimed to test the soft tissue response to a volume-stable new collagen matrix. The device demonstrated good stability during six different time points ranging from 0 to 90 days of healing with no alteration of the wound-healing processes. The 90-day histologic specimen demonstrates eventual replacement of most of the matrix with new connective tissue fibers.

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